diff --git a/.github/workflows/patch-mariadb-tests.yml b/.github/workflows/patch-mariadb-tests.yml
index 224e380925..9eb08be94e 100644
--- a/.github/workflows/patch-mariadb-tests.yml
+++ b/.github/workflows/patch-mariadb-tests.yml
@@ -59,7 +59,7 @@ jobs:
         uses: actions/cache@v2
         with:
           path: ~/.cache/pip
-          key: ${{ runner.os }}-pip-${{ hashFiles('**/requirements.txt') }}
+          key: ${{ runner.os }}-pip-${{ hashFiles('**/*requirements.txt', '**/pyproject.toml', '**/setup.py') }}
           restore-keys: |
             ${{ runner.os }}-pip-
             ${{ runner.os }}-
diff --git a/.github/workflows/server-mariadb-tests.yml b/.github/workflows/server-mariadb-tests.yml
index 48104b8f16..33fc221e80 100644
--- a/.github/workflows/server-mariadb-tests.yml
+++ b/.github/workflows/server-mariadb-tests.yml
@@ -70,7 +70,7 @@ jobs:
         uses: actions/cache@v2
         with:
           path: ~/.cache/pip
-          key: ${{ runner.os }}-pip-${{ hashFiles('**/requirements.txt') }}
+          key: ${{ runner.os }}-pip-${{ hashFiles('**/*requirements.txt', '**/pyproject.toml', '**/setup.py') }}
           restore-keys: |
             ${{ runner.os }}-pip-
             ${{ runner.os }}-
diff --git a/.github/workflows/server-postgres-tests.yml b/.github/workflows/server-postgres-tests.yml
index 241b7ddf96..2b4a2edae0 100644
--- a/.github/workflows/server-postgres-tests.yml
+++ b/.github/workflows/server-postgres-tests.yml
@@ -73,7 +73,7 @@ jobs:
         uses: actions/cache@v2
         with:
           path: ~/.cache/pip
-          key: ${{ runner.os }}-pip-${{ hashFiles('**/requirements.txt') }}
+          key: ${{ runner.os }}-pip-${{ hashFiles('**/*requirements.txt', '**/pyproject.toml', '**/setup.py') }}
           restore-keys: |
             ${{ runner.os }}-pip-
             ${{ runner.os }}-
diff --git a/.github/workflows/ui-tests.yml b/.github/workflows/ui-tests.yml
index 06ad921a6a..08bf3584f5 100644
--- a/.github/workflows/ui-tests.yml
+++ b/.github/workflows/ui-tests.yml
@@ -69,7 +69,7 @@ jobs:
         uses: actions/cache@v2
         with:
           path: ~/.cache/pip
-          key: ${{ runner.os }}-pip-${{ hashFiles('**/requirements.txt') }}
+          key: ${{ runner.os }}-pip-${{ hashFiles('**/*requirements.txt', '**/pyproject.toml', '**/setup.py') }}
           restore-keys: |
             ${{ runner.os }}-pip-
             ${{ runner.os }}-
diff --git a/frappe/utils/boilerplate.py b/frappe/utils/boilerplate.py
index 28eefd0085..edb742feb4 100644
--- a/frappe/utils/boilerplate.py
+++ b/frappe/utils/boilerplate.py
@@ -490,7 +490,7 @@ jobs:
         uses: actions/cache@v2
         with:
           path: ~/.cache/pip
-          key: ${{{{ runner.os }}}}-pip-${{{{ hashFiles('**/*requirements.txt') }}}}
+          key: ${{{{ runner.os }}}}-pip-${{{{ hashFiles('**/*requirements.txt', '**/pyproject.toml', '**/setup.py', '**/setup.cfg') }}}}
           restore-keys: |
             ${{{{ runner.os }}}}-pip-
             ${{{{ runner.os }}}}-