diff --git a/pyproject.toml b/pyproject.toml
index cbfbe53c4c..038a15cc02 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -35,7 +35,7 @@ dependencies = [
     "bleach[css]~=6.2.0",
     "chardet~=5.2.0",
     "croniter~=6.0.0",
-    "cryptography~=45.0.4",
+    "cryptography~=46.0.2",
     "cssutils~=2.11.1",
     "email-reply-parser~=0.5.12",
     "gunicorn @ git+https://github.com/frappe/gunicorn@bb554053bb87218120d76ab6676af7015680e8b6",
@@ -54,7 +54,7 @@ dependencies = [
     "premailer~=3.10.0",
     "psutil~=7.0.0",
     "psycopg2-binary~=2.9.1",
-    "pyOpenSSL~=25.1.0",
+    "pyOpenSSL~=25.3.0",
     "pydantic~=2.12.0",
     "pyotp~=2.9.0",
     "python-dateutil~=2.9.0",